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12. Dez. 2019OÄ Dr. Sabine Burger

ASH 2019: Erstes kuratives Konzept bei Multiplem Myelom?

OÄ Dr. Sabine Burger von der 3. Medizinischen Abteilung am Hanusch-Krankenhaus gibt einen Überblick über die neuen Myelom-Studien vom ASH 2019, darunter ein möglicherweise kuratives Konzept und eine neue Methode, die Patienten häufige Knochenmarkspunktionen ersparen könnte.

Quelle: ASH Annual Meeting 2019

Abstracts, die im Video diskutiert werden: 

Vorhees P et al., Abstract 691
Depth of Response to Daratumumab (DARA), Lenalidomide, Bortezomib, and Dexamethasone (RVd) Improves over Time in Patients (pts) with Transplant-Eligible Newly Diagnosed Multiple Myeloma (NDMM): Griffin Study Update

Moreau P et al., Abstract 692
Evaluation of the Prognostic Value of Positron Emission Tomography-Computed Tomography (PET-CT) at Diagnosis and Follow-up in Transplant-Eligible Newly Diagnosed Multiple Myeloma (TE NDMM) Patients Treated in the Phase 3 Cassiopeia Study: Results of the Cassiopet Companion Study

Bahlis N et al., Abstracts 1875
Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplant: Updated Analysis of Maia

Scheid C et al., Abstract 3308
Bortezomib-Based Induction and Maintenance Overcomes the Negative Prognostic Impact of Renal Impairment and del17p in Transplant-Eligible Myeloma Patients: Long Term Results from the Phase III HOVON-65/GMMG-HD4 Study after Median 137 Months Follow up

Costa LJ et al., Abstract 3125
Overall Survival of Triple Class Refractory, Penta-Exposed Multiple Myeloma (MM) Patients Treated with Selinexor Plus Dexamethasone or Conventional Care: A Combined Analysis of the STORM and Mammoth Studies

Madduri D et al., Abstract 577
Results from CARTITUDE-1: A Phase 1b/2 Study of JNJ-4528, a CAR-T Cell Therapy Directed Against B-Cell Maturation Antigen (BCMA), in Patients with Relapsed and/or Refractory Multiple Myeloma (R/R MM)