Prim. Priv.-Doz. Dr. Anton Ponholzer, F.E.B.U., Abteilung für Urologie und Andrologie, KH Barmherzige Brüder Wien, stellt die Ergebnisse dreier Studien vor, die das Vorgehen in der Praxis verändern werden. Eine vierte Studie bestätigt das derzeitige Wissen zu Kombinationstherapien.

Abstracts

Armstrong, Andrew J. et al., Abstract 5048
ARCHES: Efficacy of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (mHSPC)
Sweeney, Christopher et al., Abstract LBA2
Overall survival (OS) results of a phase III randomized trial of standard-of-care therapy with or without enzalutamide for metastatic hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led international cooperative group trial
Chi, Kim N. et al., Abstract 5006
First results from TITAN: A phase III double-blind, randomized study of apalutamide (APA) versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT)
Morris, Michael J. et al., Abstract 5008
Alliance A031201: A phase III trial of enzalutamide (ENZ) versus enzalutamide, abiraterone, and prednisone (ENZ/AAP) for metastatic castration resistant prostate cancer (mCRPC)

Uro-Onkologie