OA Dr. Kilian Gust, Universitätsklinik für Urologie, Wien, berichtet aus Chicago über den erfolgreichen Einsatz von Enfortumab Vedotin beim vorbehandelten metastasierten Blasenkarzinom. Weitere neue Daten untermauern Gemcitabin/Cisplatin als Standard und zeigen einen PFS-Vorteil mit Pembrolizumab als Erhaltungstherapie.

Abstract LBA4505
EV-201: Results of enfortumab vedotin monotherapy for locally advanced or metastatic urothelial cancer previously treated with platinum and immune checkpoint inhibitors.
Daniel Peter Petrylak

Abstract 4503
CALGB 90601 (Alliance): Randomized, double-blind, placebo-controlled phase III trial comparing gemcitabine and cisplatin with bevacizumab or placebo in patients with metastatic urothelial carcinoma.
Jonathan E. Rosenberg

Abstract 4504
Randomized double-blind phase II study of maintenance pembrolizumab versus placebo after first-line chemotherapy in patients (pts) with metastatic urothelial cancer (mUC): HCRN GU14-182.
Matt D. Galsky

Poster Board: #345, Abstract 4519
Clinical outcomes according to PD-L1 status and age in the prospective international SAUL study of atezolizumab (atezo) for locally advanced or metastatic urothelial carcinoma (UC) or non-UC of the urinary tract.
Cora N. Sternberg, MD

Uro-Onkologie