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The frozen-thawed embryo transfer timing determined by serum progesterone level: a retrospective follow-up study.

Eur J Obstet Gynecol Reprod Biol. 2014 Oct;181:210-3. doi: 10.1016/j.ejogrb.2014.07.012. Epub 2014 Jul 30.

Dong Z1, Sun L2, Zhang H3, Chen Z1, Jian Y1.
Author information 1Reproductive Medicine Center, Guangzhou Women and Children’s Medical Center, No. 9, Jinsui Road, Guangzhou 510623, Guangdong, People’s Republic of China.2Reproductive Medicine Center, Guangzhou Women and Children’s Medical Center, No.
Eur J Obstet Gynecol Reprod Biol
ABSTRACT
AbstractOBJECTIVE: To compare the reproductive outcomes of frozen-thawed embryo transfer (FET) in nature cycle utilizing monitoring ovulation regimen (MOR) and monitoring progesterone (P) level regimen (MPR).STUDY DESIGN: A retrospective analysis of records of 224 women who received FET procedures.RESULT(S): MPR was used in 60.3% (135/224) of cycles and MOR in 39.7% (89/224) of cycles. The clinical pregnancy rate per transfer was 63.0% in the MPR group and 48.3% in the MOR group (p=0.030). The implantation rates were 42.6% and 35.1%, respectively (p=0.001). The ongoing pregnancy rates per transfer (at 12 weeks’ gestation) were 54.1% and 41.6%, respectively (p>0.05). A logistic regression analysis showed that the type of natural cycle regimen was a predictor of clinical pregnancy rate (odds ratio, 1.996; 95% confidence interval, 1.123-3.549; p=0.019). Other significant variables affecting clinical pregnancy rate was number of top-quality embryos transferred.CONCLUSION(S): Performing FET using MPR could achieve higher clinical pregnancy rate compared with MOR in a group of patients with the comparable demographic and cycle characteristics profile.Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Full Text Source: Elsevier Science
PMID:25171265 | http://www.ncbi.nlm.nih.gov/pubmed/25171265

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