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Clinical predictive criteria associated with live birth following elective single embryo transfer.

Eur J Obstet Gynecol Reprod Biol. 2014 Oct;181:229-32. doi: 10.1016/j.ejogrb.2014.08.004. Epub 2014 Aug 13.

Sifer C1, Herbemont C2, Adda-Herzog E3, Sermondade N4, Dupont C4, Cedrin-Durnerin I3, Poncelet C3, Levy R4, Grynberg M3, Hugues JN3.
Author information 1Service d’Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique – Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris Cité, Unité de
Eur J Obstet Gynecol Reprod Biol
ABSTRACT
AbstractOBJECTIVE: We aimed to define clinical criteria from the patients related to the occurrence of live birth in case of elective single embryo transfer (eSET).STUDY DESIGN: We analyzed retrospectively 409 eSET at day 2/3 between March 2005 and July 2012, proposed in case of (i) woman’s age <37 years, (ii) first/second IVF0 cycle, (iii) =2 good quality embryos obtained (3-5/6-10 blastomeres at day 2/3 and <20% fragmentation), including one top embryo (4/8 cells). In all, 124/409 live births (30.3%) were obtained, separating patients into groups of women who had birth or not. Different clinical parameters of interest were compared between each group, using appropriate statistical tests at p<0.05 significance level.RESULTS: By comparing Body Mass Index (BMI), we report a statistically higher BMI among women who did not deliver (24.6 vs. 23.4kg/m(2); p=0.014). Using an analysis by BMI categories, we also precise a threshold of BMI=30kg/m(2), negatively associated with the occurrence of live birth.CONCLUSION: BMI appears to be the only clinical parameter statistically associated with delivery following eSET strategy in a good prognosis infertile population.Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Full Text Source: Elsevier Science
PMID:25171268 | http://www.ncbi.nlm.nih.gov/pubmed/25171268

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