Menü Logo medONLINE.at

Role of endometrial concentrations of heavy metals (cadmium, lead, mercury and arsenic) in the aetiology of unexplained infertility.

Eur J Obstet Gynecol Reprod Biol. 2014 Aug;179:187-90. doi: 10.1016/j.ejogrb.2014.05.039. Epub 2014 Jun 5.

Tanrikut E1, Karaer A2, Celik O1, Celik E1, Otlu B1, Yilmaz E1, Ozgul O1.

Eur J Obstet Gynecol Reprod Biol
ABSTRACT
AbstractOBJECTIVE: To determine the role of endometrial concentrations of heavy metals (cadmium, lead, mercury and arsenic) in the aetiology of unexplained infertility.STUDY DESIGN: Thirty-three women with unexplained infertility and 32 fertile women were recruited. Endometrial biopsies were collected during the putative window of implantation (cycle days 20-24). The concentrations of cadmium, lead, mercury and arsenic were measured in endometrial biopsy specimens using atomic absorption spectrometry.RESULTS: Cadmium was detected in 91% (30/33) of women with unexplained infertility, compared with 34% (11/32) of fertile women. The median endometrial cadmium concentration was 19.58 (interquartile range 1.46-30.23)µg/l in women with unexplained infertility, compared with 0.00 (interquartile range 0.00-0.40)µg/l in fertile women. Lead was detected in 15% (5/33) of women with unexplained infertility and 3% (1/32) of fertile women. Mercury and arsenic were not detected in any endometrial samples from either group.CONCLUSION: A significant difference in endometrial cadmium concentration was found between women with unexplained infertility and fertile women. This suggests that cadmium may be a contributing factor in the aetiology of unexplained infertility.Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Full Text Source: Elsevier Science
PMID:24966000 | http://www.ncbi.nlm.nih.gov/pubmed/24966000

Um den vollständigen Inhalt zu sehen, müssen Sie sich einloggen oder sich auf medONLINE.at registrieren.

Jetzt einloggen

Passwort vergessen

Jetzt kostenlos registrieren

Mit einer Anmeldung bei medONLINE.at haben Sie Zugriff auf: DFP-Kurse, Arzneimittelinfos, Produktfortbildungen und mehr.

Loggen Sie sich ein oder registrieren Sie Ihren kostenlosen medONLINE.at Account.